NCT05429827

The Therapeutic Effects of Dextrose Injection for Myofascial Pain Syndrome

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: National Cheng-Kung University Hospital · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

Patients with an myofascial trigger point (MTrP) in their upper trapezius will be divided into three groups: Group A receiving MTrP injection with normal saline (control group), Group B with hypo-osmolar dextrose (5% dextrose), and Group C with hyper-osmolar dextrose (15% dextrose). Clinical outcomes and morphological changes will be measured before the injection, one hour after, one week after, two weeks after, and one month after the injection to delineate the therapeutic effects of dextrose injection for an MTrP.

Detailed description

This experiment is designed to evaluate the therapeutic effects of dextrose injection on an myofascial trigger point (MTrP). Patients with an MTrP in their upper trapezius will be recruited and be divided into three groups: Group A receiving MTrP injection with normal saline (control group), Group B with hypo-osmolar dextrose (5% dextrose), and Group C with hyper-osmolar dextrose (15% dextrose). Clinical outcomes (visual analog scale, pressure pain threshold, range of motion, neck disability index) will be measured before the injection, one hour after, one week after, two weeks after, and one month after the injection. Morphological changes of an MTrP before, and after the injection will also be evaluated by sonography. Through this study, the definite therapeutic effects, and the better osmolality of dextrose injection for the treatment of an MTrP will be delineated.

Conditions

• Myofascial Trigger Point Pain

Interventions

Type	Name	Description
OTHER	normal saline	Inject 2 ml normal saline into a myofascial trigger point and evaluate the clinical effects before and after the injection.
DRUG	Dextrose 5% in water	Inject 2 ml 5% dextrose into a myofascial trigger point and evaluate the clinical effects before and after the injection.
DRUG	Dextrose 15% in water	Inject 2 ml 15% dextrose into a myofascial trigger point and evaluate the clinical effects before and after the injection.

Timeline

• Start date: 2022-11-18
• Primary completion: 2025-12-20
• Completion: 2025-12-31
• First posted: 2022-06-23
• Last updated: 2025-01-01

Locations

1 site across 1 country: Taiwan