Trials / Active Not Recruiting
Active Not RecruitingNCT05421806
A Cohort Study of Use of Doravirine (DOR) Based Regimens in Clinical Practice in Europe DoRavirine Europe Real World/
A Cohort Study of Use of Doravirine (DOR) Based Regimens in Clinical Practice in Europe
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 500 (estimated)
- Sponsor
- NEAT ID Foundation · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Following the initiation of Doravirine (DOR) regimen among people living with HIV (PLWH), the study will aim to assess effectiveness, discontinuation, and resistance over the 12-month period. Retrospective data from 500 patients is planned to be collected from 6 - 10 European sites. Cohort 1 : 400 patients, 100 treatment naïve and 300 virally suppressed patients switching from a 1st or second line treatment, Cohort 2: 50 patients with NNRTI mutations (other than DOR), Cohort 3: 50 patients with NNRTI mutations (including DOR). The study will be conducted through collaboration with the NEAT ID Network, a well-established network of clinical sites across Europe.
Conditions
Timeline
- Start date
- 2022-10-10
- Primary completion
- 2026-03-06
- Completion
- 2026-05-01
- First posted
- 2022-06-16
- Last updated
- 2025-12-30
Locations
19 sites across 5 countries: Belgium, France, Netherlands, Spain, United Kingdom
Source: ClinicalTrials.gov record NCT05421806. Inclusion in this directory is not an endorsement.