NCT05421780

Post-prandial Glycaemic Controlling Effects of BSG in Singapore Adults With Metabolic Syndrome

Impact of Brewer's Spent Grain (BSG) and Bio-transformed BSG Biscuits on Post-prandial Glycaemic Controlling Effects in Singapore Adults With Metabolic Syndrome

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: National University of Singapore · Academic / Other
• Sex: All
• Age: 35 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to assess the glycaemic controlling effects of BSG and bio-transformed BSG-containing biscuits in Singapore adults with MetS. The investigators hypothesized that consumption of BSG and bio-transformed BSG containing biscuit will improve glycaemic control.

Detailed description

This is a double-blind, randomised, crossover experiment. During the 3-week, 19 subjects will participate in a 3 meal tolerance test (MTT). During each MTT session, all subjects are required to consume 90 g biscuits (either control, autoclaved BSG or bio-transformed BSG biscuits) and monitored over a period of 240 minutes. All three types of biscuits will be consumed at a randomised sequence during this 3-week period. Post-prandial blood glucose, insulin, lipid and amino acid responses, breath analysis, body composition, blood pressure, appetite assessment, and any other glycaemic biomarkers will be assessed.

Conditions

• Metabolic Syndrome
• Diabetes
• Diet Modification

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	autoclaved BSG-containing biscuits	Consumption of autoclaved BSG-containing biscuits as breakfast.
DIETARY_SUPPLEMENT	bio-transformed BSG-containing biscuits	Consumption of bio-transformed BSG-containing biscuits as breakfast.
DIETARY_SUPPLEMENT	control biscuits	Consumption of plain biscuits as breakfast.

Timeline

• Start date: 2022-06-29
• Primary completion: 2022-12-13
• Completion: 2024-07-01
• First posted: 2022-06-16
• Last updated: 2023-11-09

Locations

1 site across 1 country: Singapore