NCT05420610

Early Goal-Directed Therapy Utilizing Transpulmonary Thermodilution and Severe Burn Injury

Early Goal-Directed Therapy Utilizing Transpulmonary Thermodilution for Treating Adult Patients With Severe Burn Injury

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 66 (actual)
• Sponsor: Chang Gung Memorial Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

This study aimed to optimize fluid resuscitation with transpulmonary thermodilution (TPTD)-guided protocol and to lower the mortality rate of the severely burned.

Conditions

• Burns

Interventions

Type	Name	Description
OTHER	Control group: Patients being admitted when The advancement of transpulmonary thermodilution(TPTD) device was unavailable.	The control group included patients being admitted when TPTD device was unavailable; and relatively stable patients without the need for TPTD. The adequacy of fluid resuscitation in the control group was monitored by traditional monitoring parameters including vital signs and hourly urine output.
OTHER	Study group: TPTD device was implemented for monitoring.	TPTD device was implemented for monitoring; the inclusion criteria included patients suffering from 2nd degree burn greater than 40% TBSA; a combined 2nd to 3rd degree burn greater than 30% TBSA; or patients with inhalation injury despite the burned surface area.

Timeline

• Start date: 2021-08-07
• Primary completion: 2021-11-30
• Completion: 2022-01-20
• First posted: 2022-06-15
• Last updated: 2022-06-15

Locations

1 site across 1 country: Taiwan