NCT05417672

Assessment of Relationship Between Preoperative Nutritional Status and Perioperative/Postoperative Conditions in Patients With Lung Cancer Scheduled for Lobectomy

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 63 (estimated)
• Sponsor: Turkish Society of Anesthesiology and Reanimation · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Malnutrition is common in patients with lung cancer. In patients with malnutrition risk, the risk of complications is high both in the perioperative, early and late postoperative periods. Malnutrition is an independent risk factor for length of hospital stay and cost in these patients. Patients with lung cancer may have many morbidities in postoperative period, especially problems with wound healing. Therefore, assessment of the nutritional status of patients with lung cancer should begin at the diagnosis stage.

Detailed description

In patients with lung cancer scheduled for lobectomy, anthropometric measurements will be measured and the results of laboratory tests(albumin, prealbumin, creatinine, total lymphocyte count, C reactive protein), Nutritional Risk Screening-2002, Nutritional Risk Index, Mini Nutritional Assessment, Glasgow Prognostic Score, Prognostic Nutritional Index and neoadjuvant chemotherapy or not will be recorded in 72 hours before surgery. In addition, demographic information of the patients (name, surname, identification number, age, comorbidity, American Society of Anesthesiologists score) will be recorded. After the information is given to the patients, their written and verbal consent will be obtained. In the operating room, routine monitoring (electrocardiography, invasive blood pressure measurement, arterial blood gas monitoring, peripheral oxygen saturation, end-tidal carbon dioxide measurement by capnography) will be applied to the patients in accordance with the standard protocol for elective lobectomy surgery. Hemodynamic changes (eg. dysrhythmia, hypotension, hypertension, hemorrhage), metabolic status (pH, bicarbonate, base excess), lactate, glucose level in blood gas evaluation and intraoperative complications will be recorded during the intraoperative period. In the postoperative period, length of stay in the intensive care unit, length of hospital stay, early complications (eg. dysrhythmia, acute coronary syndrome, sepsis, mediastinitis, pneumonia, surgical site infection, prolonged air leak), time to start oral intake and transition to adequate oral intake will be recorded in the one-month postoperative period.

Conditions

• Lung Cancer
• Malnutrition
• Nutritional Deficiency

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Nutritional Risk Screening-2002	Nutritional Risk Screening-2002
DIAGNOSTIC_TEST	Nutritional Risk Index	Nutritional Risk Index
DIAGNOSTIC_TEST	Mini Nutritional Assessment	Mini Nutritional Assessment
DIAGNOSTIC_TEST	Glasgow Prognostic Score	Glasgow Prognostic Score
DIAGNOSTIC_TEST	Prognostic Nutritional Index	Prognostic Nutritional Index
DIAGNOSTIC_TEST	Anthropometric measurements	middle arm circumference
DEVICE	Handgrip strength test	Handgrip strength test

Timeline

• Start date: 2021-09-29
• Primary completion: 2022-06-08
• Completion: 2022-09-01
• First posted: 2022-06-14
• Last updated: 2022-06-14

Locations

1 site across 1 country: Turkey (Türkiye)