NCT05415904

Hantavirus Nephropathy in North-Eastern France : Severity Risk Factors and Prognostic Tools

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 101 (actual)
• Sponsor: Central Hospital, Nancy, France · Academic / Other
• Sex: All
• Age: 18 Years – 125 Years
• Healthy volunteers: Not accepted

Summary

Hantaviruses are emerging pathogens responsible for hemorrhagic fever with renal syndrome. Severity risks factors aren't consensual in litterature, mostly related to scandinavian cohorts. A prognostic score was created to help patient's orientation in healthcare system but wasn't independantly validated (Hentzien, Emerging infectious diseases 2018). This retrospective cohort of hantavirus infected hospitalized adults patients in the north-eastern quarter of France between 2013 and 2022 will specify the kidney damage during infection and risk factors for a severe form (defined par acute kidney injury KDIGO 3). The previous prognostic score performance will be evaluated in this cohort.

Conditions

• Hantavirus Nephropathy
• Hantavirus Infection

Interventions

Type	Name	Description
OTHER	HANTA-NE	Observational cohort study

Timeline

• Start date: 2022-05-20
• Primary completion: 2023-10-30
• Completion: 2024-07-31
• First posted: 2022-06-13
• Last updated: 2025-02-24

Locations

1 site across 1 country: France