NCT05415696

Prostatic Artery Embolization for the Treatment of Lower Urinary Tract Symptoms in Prostate Cancer Patients Undergoing Radiation Therapy

Prostatic Artery Embolization (PAE) for the Treatment of Lower Urinary Tract Symptoms (LUTS) in Prostate Cancer Patients Undergoing Radiation Therapy

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 40 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to learn if the prostatic artery embolization procedure can reduce urinary tract symptoms in patients with enlarged prostates and prostate cancer.

Detailed description

PRIMARY OBJECTIVE 1\. To evaluate the symptomatic improvement in lower urinary tract symptoms after prostatic artery embolization (PAE) SECONDARY OBJECTIVES 1. To evaluate objective measures of improved urinary obstruction after PAE: urine flow rate, prostate volume, and post-void residual 2. To measure effects of PAE on prostate specific antigen (PSA). 3. To evaluate if PAE reduces the prostate volume and simplifies radiation therapy 4. To evaluate the safety of PAE performed in this patient population

Conditions

• Prostate Cancer

Interventions

Type	Name	Description
PROCEDURE	Prostatic artery embolization	Patients will undergo PAE with 100-300 µm or 300-500 µm Embospheres following standard PAE technique performed by Interventional Radiology at Stanford University

Timeline

• Start date: 2023-09-19
• Primary completion: 2024-09-01
• Completion: 2024-09-01
• First posted: 2022-06-13
• Last updated: 2024-08-09

Locations

1 site across 1 country: United States