NCT05415436

Analyzing the Relationship Between Speed Propofol is Given and Low Blood Pressure

Analyzing the Relationship Between Rate of Induction and Perioperative Hypotension Using Propofol

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: University of Toledo · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The objective of this study is to evaluate the hemodynamic changes related to Propofol administration rate. We hypothesize that slow administration of IV propofol will have less hemodynamic disturbances and will require less amount of vasoactive medication for BP correction when compared to standard FDA approved administration rate.

Conditions

• Hypotension on Induction

Interventions

Type	Name	Description
OTHER	Propofol slow administration	Propofol will be slowly administered over 120 seconds by anesthesia provider

Timeline

• Start date: 2022-08-11
• Primary completion: 2023-06-30
• Completion: 2023-07-21
• First posted: 2022-06-13
• Last updated: 2025-03-21
• Results posted: 2025-03-21

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study