Clinical Trials Directory

Trials / Completed

CompletedNCT05414175

A Study of Mavacamten in Obstructive Hypertrophic Cardiomyopathy

A Phase 3, Open-label, Single Arm, Clinical Study to Evaluate Efficacy, Safety and Tolerability of Mavacamten in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
38 (actual)
Sponsor
Bristol-Myers Squibb · Industry
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to evaluate the effectiveness, safety, and tolerability of a 30-week course of mavacamten and the long-term effects of mavacamten in Japanese participants with symptomatic obstructive hypertrophic cardiomyopathy (HCM).

Conditions

Interventions

TypeNameDescription
DRUGMavacamtenSpecified dose on specified days

Timeline

Start date
2022-08-19
Primary completion
2023-11-27
Completion
2025-12-11
First posted
2022-06-10
Last updated
2026-01-27
Results posted
2024-12-04

Locations

20 sites across 1 country: Japan

Regulatory

Source: ClinicalTrials.gov record NCT05414175. Inclusion in this directory is not an endorsement.