NCT05413837

Anatomical Variation of Cerebral Venous Sinus in Healthy Individuals

Imaging Research on Anatomical Variation of Cerebral Venous Sinus in Healthy Individuals

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 40 (estimated)
• Sponsor: Capital Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The anatomical characteristics of veins and venous sinus result in great differences between cerebral venous system diseases and cerebral artery diseases in etiology, pathophysiology and clinical features.Therefore, understanding the anatomy and variation of normal venous sinuses is essential to identify the intracranial venous lesions.

Detailed description

The classification of venous sinus and its variation based on the autopsy of patients can not fully reflect the real anatomy and variation of venous sinus in human, and the targeted research on healthy people is still unknown. The main purpose of this research is to use multimodal magnetic resonance technology to study the variation of venous sinus in Chinese healthy population, to preliminarily improve the anatomical classification of venous sinus in Chinese , to verify the the correlation between venous sinus variation and various non-genetic factors at the same time, as well as establishing reliable quantitative evaluation indicators.

Conditions

• Venous Sinus Thrombosis, Cranial

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	anotomy and variation of venous sinus	Contrast enhanced-magnatic resonance venography（CE-MRV）and other magnetic resonance imaging methods are used to estimate the anatomy of cerebral venous sinus.
DIAGNOSTIC_TEST	the level of biomarker in bood	Elisa or omics analysis is used to test the level of biomarker in blood.

Timeline

• Start date: 2022-07-06
• Primary completion: 2023-08-31
• Completion: 2023-08-31
• First posted: 2022-06-10
• Last updated: 2023-04-18

Locations

1 site across 1 country: China