Trials / Completed
CompletedNCT05413720
Study of the Innate Immune Response to the Acute Phase of Human Leptospirosis - IMMUNOLEPTO
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 100 (actual)
- Sponsor
- Centre Hospitalier Universitaire de la Réunion · Academic / Other
- Sex
- All
- Age
- 4 Years
- Healthy volunteers
- Not accepted
Summary
The research hypothesis is based on a suspected strong involvement of the immune system in the genesis of serious manifestations of the disease (hepatitis, renal failure, thrombocytopenia, intra-alveolar hemorrhage). The question asked is that of the state of the immune system (quantitative and qualitative: activation markers, production of cytokines) evaluated by the study of circulating innate immune cells (monocytes, neutrophils, dendritic cells, lymphocytes, platelets).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | two additional blood samples specific to research | proportion of activated monocyte cells (CD14+CD16+ phenotype) within monocytes in the acute phase |
Timeline
- Start date
- 2021-01-06
- Primary completion
- 2022-07-20
- Completion
- 2022-07-20
- First posted
- 2022-06-10
- Last updated
- 2023-10-25
Locations
4 sites across 1 country: Reunion
Source: ClinicalTrials.gov record NCT05413720. Inclusion in this directory is not an endorsement.