NCT05410795

Establishment and Verification of Pancreatic Volume Formula Based on Imaging

Establishment and Verification of Pancreatic Volume Formula Based on Imaging: A Cross-sectional Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 300 (estimated)
• Sponsor: Changhai Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: —

Summary

This study intends to construct the linear relationship between pancreatic volume and individual attributes (height, weight, width of anterior superior iliac spine, etc.), and to establish and verify the formula of pancreatic volume.

Detailed description

The volume of pancreas in healthy individuals changes with age. The pancreatic volume gradually increases from birth to 20 years old. There is a plateau period from 20 to 60 years old, and the volume gradually decreases after 60 years old. With the development of imaging technology, pancreatic volume can be measured by computer tomography and magnetic resonance imaging. Whether it is pancreatic atrophy after chronic pancreatitis or pancreatic edema after acute pancreatitis, the pathological changes of pancreatic parenchyma may lead to changes in pancreatic volume. Many studies have confirmed that pancreatic volume can be used to evaluate the course of pancreatic related diseases such as diabetes and acute pancreatitis. Therefore, the establishment of accurate and convenient pancreatic volume formula can help to estimate the initial pancreatic volume of patients. This study is helpful to evaluate the clinical stage, severity and prognosis of pancreatic related diseases.

Conditions

• Healthy People
• Chronic Pancreatitis
• Acute Pancreatitis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Magnetic resonance imaging	Enrolled subjects will be examined with MRI of pancreas, and the volume, length and thickness of coronal plane of pancreas will be measured by software.

Timeline

• Start date: 2022-09-05
• Primary completion: 2022-09-05
• Completion: 2022-12-01
• First posted: 2022-06-08
• Last updated: 2022-09-14

Locations

1 site across 1 country: China