NCT05409885

The Effect of General and Spinal Anesthesia on Neutrophil-to-lymphocyte Ratio

Comparison of the Effect of General and Spinal Anesthesia on Umbilical Neutrophil-to-lymphocyte Ratio, Platelet-to-lymphocyte Ratio and Mean Platelet Volume in Patients Undergoing Cesarean Section

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 60 (actual)
• Sponsor: Antalya Training and Research Hospital · Other Government
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study was to evaluate the effects of anesthetic techniques (general and spinal anesthesia) on umbilical cord neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume (MPV) in patients undergoing cesarean section.

Detailed description

This study was designed to evaluate the effects of anesthetic techniques (general and spinal anesthesia) on umbilical cord NLR, PLR and MPV in patients undergoing cesarean section. The primary endpoint was to compare the effects of general and spinal anesthesia on umbilical cord NLR. Secondary endpoints were determined the general and spinal anesthesia on routine umbilical cord PLR, MPV and newborn Apgar scores at 1st and 5th min.

Conditions

• Anesthesia, General
• Anesthesia, Spinal
• Umbilical Cord

Interventions

Type	Name	Description
OTHER	General anesthesia	Evaluate the effects of general anesthesia on NLR, PLR and MPV in patients undergoing cesarean section.
OTHER	Spinal anesthesia	Evaluate the effects of spinal anesthesia on NLR, PLR and MPV in patients undergoing cesarean section.

Timeline

• Start date: 2022-03-20
• Primary completion: 2022-07-01
• Completion: 2022-07-07
• First posted: 2022-06-08
• Last updated: 2022-07-21

Locations

1 site across 1 country: Turkey (Türkiye)