Trials / Completed
CompletedNCT05407740
"Association of Proteinuria and Progression of Kidney Dysfunction in Sickle Cell Disease"Disease
"ASsociation of Proteinuria and Progression of KidneY DysfunctioN in Sickle Cell Disease"
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 355 (actual)
- Sponsor
- Soutien aux Actions contre les Maladies du Globule Rouge · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
To describe change in ACR and eGFR during study follow-up, and assesss the association of baseline and change in ACR and eGFR, with progression of kidney failure and/or all-cause mortality.
Detailed description
This is a retrospective, non-interventional, secondary use of the data coming from the single-center secondary GEN-MOD study cohort at the Henri Mondor Hospital (Creteil, France). The GEN-MOD cohort includes 355 SCD patients. The GEN-MOD data are accessible through the center's clinical and laboratory database and will be extracted and analyzed for the purpose of this study. The enrolment in the GEN-MOD cohort lasted from 01 December 2002 until 01 March 2014. Follow-up occurred every six months and ranged from five to seventeen years and ended on 31 December 2019. The index date (baseline) for this study is the time of inclusion of patients in GEN-MOD cohort study
Conditions
- Change in Albumin to Creatinine Ratio and Glomerular Filtration Rate
- Progression of Kidney Failure and or All-cause Mortality
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | no intervention study | no intervention study |
Timeline
- Start date
- 2021-03-01
- Primary completion
- 2021-03-01
- Completion
- 2021-12-01
- First posted
- 2022-06-07
- Last updated
- 2024-05-16
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT05407740. Inclusion in this directory is not an endorsement.