NCT05401344

The Objective Assessment and Characteristics of Dry Nose From Clinical Perspective

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 120 (actual)
• Sponsor: Beijing Tongren Hospital · Academic / Other
• Sex: All
• Age: 23 Years – 73 Years
• Healthy volunteers: Accepted

Summary

In the present study, we propose objective diagnostic criteria for dry nose (DN) and investigate its characteristics. Questionnaires were completed by each participant during recruitment to record demographic data. DN test strips were used to evaluate the severity of DN at five time points and allergic status was assessed based on serum sIgE levels. Nasal secretions were collected and vasomotor rhinitis was diagnosed using the cold dry air test. The diagnosis of allergic rhinitis (AR) was based on the criteria of the Allergic Rhinitis and its Impact on Asthma consensus statement. Data are expressed as median and interquartile range, unless otherwise specified. Statistical significance was set at P \< 0.05. The reference range (RR) of the 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentiles were determined for each test strip length at each time point. This study aimed to investigate the characteristics of and propose objective diagnostic criteria for DN.

Conditions

• Diagnostic Self Evaluation

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	test strips,sponges and cold dry air test	Test strips were used to evaluated the degree of dry nose, sponges were used to obtain the nasal secretion and cold dry air test was used to making diagnosis of vasomotor rihinitis.

Timeline

• Start date: 2018-12-11
• Primary completion: 2021-07-24
• Completion: 2021-10-31
• First posted: 2022-06-02
• Last updated: 2022-06-02

Locations

1 site across 1 country: China