Clinical Trials Directory

Trials / Terminated

TerminatedNCT05399368

An Efficacy and Safety Study of RPT193 in Adults With Atopic Dermatitis

A Phase 2 Study to Evaluate the Efficacy and Safety of RPT193 as Monotherapy in Adults With Moderate-to-Severe Atopic Dermatitis

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
229 (actual)
Sponsor
RAPT Therapeutics, Inc. · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

Phase 2 study of RPT193 in adults with atopic dermatitis

Detailed description

Randomized, placebo-controlled Phase 2 study of RPT193 in adults with moderate-to-severe atopic dermatitis

Conditions

Interventions

TypeNameDescription
DRUGRPT193RPT193 is an antagonist of the C-C motif chemokine receptor 4 (CCR4) that inhibits CCR4-mediated chemotaxis toward both CCL22 and CCL17
OTHERPlaceboNonactive placebo tablet

Timeline

Start date
2022-06-07
Primary completion
2024-05-24
Completion
2024-05-24
First posted
2022-06-01
Last updated
2026-03-23
Results posted
2026-02-25

Locations

59 sites across 2 countries: United States, Canada

Regulatory

Source: ClinicalTrials.gov record NCT05399368. Inclusion in this directory is not an endorsement.