NCT05398744

Motivational Interviewing and Group Heart Transplant Exercise and Education: A Pilot Study

MIGHTEE: Motivational Interviewing and Group Heart Transplant Exercise and Education: A Pilot Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 23 (actual)
• Sponsor: Children's Hospital of Philadelphia · Academic / Other
• Sex: All
• Age: 12 Years – 18 Years
• Healthy volunteers: Accepted

Summary

The aim of this 16-week group aerobic training program, delivered remotely via video-conferencing, is to assess program feasibility, and determine if program increases physical activity in adolescents after heart transplant.

Detailed description

Orthotopic heart transplant (OHT) is the definitive therapy for children with cardiac disease, however, survival after transplant is limited, and quality of life after transplant is less than healthy peers'. The transplanted heart usually works well, pumping blood as well as most healthy hearts. As such, the American Heart Association recommends no specific exercise related restrictions for heart transplant recipients. Although most children have normal cardiac function after OHT, children with transplanted hearts have impaired exercise performance, and do not exercise as much as their peers. This finding is concerning, as impaired exercise tolerance is associated with reduced survival, diminished health related quality of life, and depression and anxiety. These factors negatively impact adherence, and further limit graft survival. Thus, identifying interventions that positively impact physical activity and promote graft longevity, like individualized exercise programs, should be a priority for post-transplant care. Investigators propose that increasing physical activity in children and adolescents after OHT may be a critical modifiable method for increasing graft longevity and improving quality of life. Investigators will explore this through a pilot program. Participants will wear an activity monitor to record physical activity, parents/caregivers and participants will complete surveys, and participants will engage with psychologists and exercise physiologists.

Conditions

• Orthotopic Heart Transplant

Interventions

Type	Name	Description
OTHER	Group Exercise Program	At-home, aerobic group exercise program facilitated by exercise physiologist via video format, 3 times a week for 16 weeks.

Timeline

• Start date: 2022-07-13
• Primary completion: 2024-06-06
• Completion: 2024-06-26
• First posted: 2022-06-01
• Last updated: 2024-09-24

Locations

1 site across 1 country: United States