NCT05397262

Organ-preservative Therapy of Bladder Cancer With Radiotherapy or Radiochemotherapy Combined With Hyperthermia

Register-Trial Based on an Agreement of Health Insurances With the Department of Radiation Therapy of the University Hospital Erlangen for the Application of Regional Hyperthermia in Bladder Cancer: Organ-preservative Therapy of Bladder Cancer With Radiotherapy or Radiochemotherapy Combined With Hyperthermia

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,000 (estimated)
• Sponsor: University of Erlangen-Nürnberg Medical School · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Analysis of the efficacy and the compatibility of deep regional hyperthermia in combination with radiotherapy and chemoradiotherapy in bladder cancer

Conditions

• Bladder Cancer

Interventions

Type	Name	Description
OTHER	Hyperthermia	Deep Regional Hyperthermia (RHT) 1-2/week up to 10 sessions a type of cancer treatment in which body tissue is exposed to high temperatures (up to 113°F).
RADIATION	Radiotherapy	50,4 Gy (28 x 1,8 Gy) plus Boost: If R0: 5,4 Gy; If R1/2: 9 Gy
DRUG	Chemotherapy 5-Fluorouracil	600 mg/m\^2 civ 120h; d 1-5, 29-33
DRUG	Chemotherapy Cisplatin	20 mg/m\^2; d1-5, 29-33

Timeline

• Start date: 2017-03-29
• Primary completion: 2098-12-31
• Completion: 2099-12-31
• First posted: 2022-05-31
• Last updated: 2024-05-09

Locations

1 site across 1 country: Germany