Clinical Trials Directory

Trials / Unknown

UnknownNCT05396573

A Phase 1b Trial to Evaluate the Safety and Immunogenicity of a SARS-CoV-2 mRNA Chimera Vaccine Against COVID-19

A Randomized, Blinded, Positive Control Phase 1b Trial to Evaluate the Safety and Immunogenicity of a SARS-CoV-2 mRNA Chimera Vaccine (RQ3013) in Healthy Adults Completed a Two-dose Primary Series of Inactivated Vaccine

Status
Unknown
Phase
Phase 1
Study type
Interventional
Enrollment
120 (estimated)
Sponsor
Walvax Biotechnology Co., Ltd. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

This is a phase 1b, randomized, double-blind, positive control trial in healthy adults, intended to evaluate the safety and immunogenicity profile of RQ3013 in healthy adults primed with a two-dose inactivated vaccine 6-9 months earlier. The study vaccine is administered IM in the upper arm deltoid as single booster shot on day 0.

Conditions

Interventions

TypeNameDescription
BIOLOGICALRQ3013A single dose of 30 μg/0.15 mL, a single dose of 60 μg/0.3 mL
BIOLOGICALComirnatyA single dose of 30 μg/0.3 mL

Timeline

Start date
2022-07-01
Primary completion
2022-08-01
Completion
2023-07-01
First posted
2022-05-31
Last updated
2022-05-31

Source: ClinicalTrials.gov record NCT05396573. Inclusion in this directory is not an endorsement.