NCT05394896

Hypotension Prediction With HPI Algorithm During Decessed-donor Kidney Transplant (HPI2022)

Hypotension Prediction With HPI Algorithm During Decessed-donor Kidney Transplant: an Explorative, Monocentric, RCT

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 46 (estimated)
• Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

HPI monitoring and the adoption of therapeutic interventions before hypotension occurs should be ensure a shorter time of intra-operative hypotension (MAP \< 65 mmHg) during deceased-donor kidney transplant surgery. The control group is represented by patients undergoing the same surgical procedure with hemodynamic monitoring with invasive blood pressure monitoring which represents the gold standard for this surgery. HPI monitoring has not yet been investigated during this surgery.

Conditions

• Hypotension During Surgery
• Kidney Transplant; Complications

Interventions

Type	Name	Description
DEVICE	ACUMEN (Edwards Lifesciences, Irvine, USA)	ACUMEN sensor generates HPI index which should predict hypotension. Based on HPI index, Eadyn and dP/dTmax values anaesthesia should somministrate liquid or drugs to prevent hypotension.
DEVICE	Invasive Blood Pressure	Invasive Blood Pressure permits continue monitoring of blood pressure (routine standard for kidney transplant surgery)

Timeline

• Start date: 2022-11-01
• Primary completion: 2023-11-30
• Completion: 2024-01-31
• First posted: 2022-05-27
• Last updated: 2023-01-17

Locations

1 site across 1 country: Italy