NCT05392842

Corchorus Olitorius Buccal Films for the Treatment of Recurrent Minor Aphthous Ulcerations

The Potential of Corchorus Olitorius Seeds Buccal Films for Treatment of Recurrent Minor Aphthous Ulcerations in Human Volunteers

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Deraya University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

A methanol extract of Corchorus olitorius edible plant was perpared for extration of glycosideal compounds. the extract was tested for its efficacy as antiinflammatory and analgesic activity invitro and approved by the biomarkers. a fast dissolvinf mucoadhesive film was prepared by a certain amounts of highly safe polymers for a pilote study on human for treament of Aphthous Ulcerations. two groups of study, placebo and intrvention will be recurited and followed for pain, erthymia and size of ulcers for 6 days.

Conditions

• Aphthous Ulcer Recurrent

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Corchorus Olitorius Buccal fast dissolving Films	Corchorus Olitorius Buccal fast dissolving Films
DIETARY_SUPPLEMENT	plain mucoadhesive fast dissolving film	plain mucoadhesive fast dissolving film

Timeline

• Start date: 2022-04-10
• Primary completion: 2022-06-18
• Completion: 2022-07-01
• First posted: 2022-05-26
• Last updated: 2022-10-24

Locations

1 site across 1 country: Egypt