NCT05392348

Human Gut Microbiota and microRNA Expression

Regulatory Effect of Stachyose on Gut Microbiota and microRNA Expression in Human

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 36 (estimated)
• Sponsor: Xijing Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

In this study, stachyose was used as an intervention factor. We will evaluate changes in fecal gut microbiota and miRNA expression profiles in subjects under stachyose intervention

Detailed description

In the stachyose intervention group, each person in the stachyose intervention group took 5 g of stachyose daily before breakfast, and the administration method was 100 ml of drinking water dissolved and taken orally for two months. Each person in the placebo control group took the same amount of maltodextrin daily. Stool samples of the subjects were collected weekly.

Conditions

• Gut Microbiota
• microRNA

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	stachyose	Stachyose is a tetrasaccharide consisting of sucrose having an alpha-D-galactosyl-(1-\>6)-alpha-D-galactosyl moiety attached at the 6-position of the glucose.
DIETARY_SUPPLEMENT	Maltodextrin	Maltodextrin is a polysaccharide that is used primarily in foods and beverages as a thickener, sweetener, and/or stabilizer. It is a relatively short-chain polymer (some would call it an oligomer); commercial products contain an average of ≈3 to ≈17 glucose units per chain. It is manufactured by partially hydrolyzing grain starches, usually corn or wheat.

Timeline

• Start date: 2022-05-25
• Primary completion: 2022-06-25
• Completion: 2022-06-30
• First posted: 2022-05-26
• Last updated: 2022-05-26

Locations

1 site across 1 country: China