Clinical Trials Directory

Trials / Completed

CompletedNCT05391022

Study Evaluating Food Effect and QTc in Patients With Advanced Malignancies

A Phase 1, 2-Part Study to Evaluate the Effect of Food on Pharmacokinetics of Pelabresib (CPI-0610) and the Effect of Pelabresib on QTc in Patients With Advanced Malignancies

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
35 (actual)
Sponsor
Constellation Pharmaceuticals · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Phase 1 2-part study to evaluate the effect of food on pharmacokinetics of pelabresib (CPI-0610) and the effect of pelabresib on QTc in patients with advanced malignancies

Conditions

Interventions

TypeNameDescription
DRUGPelabresibPelabresib monohydrate tablets

Timeline

Start date
2021-07-20
Primary completion
2023-03-08
Completion
2024-02-29
First posted
2022-05-25
Last updated
2025-07-28

Locations

10 sites across 3 countries: United States, Georgia, Spain

Regulatory

Source: ClinicalTrials.gov record NCT05391022. Inclusion in this directory is not an endorsement.

Study Evaluating Food Effect and QTc in Patients With Advanced Malignancies (NCT05391022) · Clinical Trials Directory