NCT05390203

Sexual Function Before and After Bariatric Surgeries.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 55 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: Male
• Age: 18 Years – 60 Years
• Healthy volunteers: —

Summary

To assess sexual function before and the impact of weight loss after bariatric surgery among obese men with sexual dysfunction.

Detailed description

Obesity is a worldwide prevalent problem which is currently considered a pandemic disease. It is intimately related to several comorbidities that negatively impact physical and mental health. Male sexual dysfunction is not uncommon in people with obesity. This could be attributed to many obesity-associated conditions as diabetes mellitus (DM), hypertension (HTN), and mental and social impairment. Obesity indirectly affects male sexual function by inducing many comorbidities associated with sexual dysfunction. Obesity is also a complex endocrine disorder that can independently alter sexual function through the disruption of various sex hormones. Men with morbid obesity often suffer from deep but reversible sexual dysfunction. Several managements have been introduced to deal with obesity. Dietary intervention, medications, physical exercise are widely used in case of mild and moderate obesity. Meanwhile, bariatric surgery has become the most effective treatment strategy for morbid obese patients which can bring great weight reduction and is expected to ameliorate the comorbidities. Mora et al.'s prospective study showed a bariatric surgery-related significant increase in the IIEF score at 1 year postoperatively. This was found also by the Groutz et al. and Kun et al. However, in a retrospective study by Rosenblatt et al., there was no significant increase in the IIEF scores following RYGB surgery in 23 male patients. Similarly, Sarwer et al., in their prospective study, found that despite the increased postoperative IIEF scores, this difference lied out of significance except for the overall satisfaction.

Conditions

• Sexual Dysfunction

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Penile duplex study, Hormonal Assay (Total Testosterone, Prolactin and E2)	we will do penile duplex and hormonal profile preoperatively and 6 months postoperatively.

Timeline

• Start date: 2022-08-01
• Primary completion: 2024-08-01
• Completion: 2024-10-01
• First posted: 2022-05-25
• Last updated: 2022-05-25