Clinical Trials Directory

Trials / Completed

CompletedNCT05386459

Study of the Use of the Drug Ingaron in Patients With COVID-19

Prospective Two-week Open-label Application Experimental Randomized Single-center Non-interventional Study of the Drug Ingaron in Patients With a New Coronavirus Infection COVID-19

Status
Completed
Phase
Study type
Observational
Enrollment
36 (actual)
Sponsor
SPP Pharmaclon Ltd. · Industry
Sex
All
Age
38 Years – 84 Years
Healthy volunteers
Not accepted

Summary

Interferon gamma is a powerful endogenous regulatory cytokine that activates the antiviral immune response, while it also has its own antiviral activity. The objective of this study was to evaluate the effectiveness of the proposed treatment regimen with Ingaron (INN: recombinant interferon gamma human, lyophilisate for preparing a solution for intramuscular and subcutaneous administration of 500,000 IU) in patients with viral pneumonia.

Detailed description

The study drug was prescribed for therapeutic purposes according to the following scheme: 500,000 IU s / c 1 time per day daily for 5 days. A total of 4 visits were scheduled. Visits 0 and 1 could be combined provided that the chronological sequence of screening and randomization procedures was followed. The main stages of the study: screening - lasting no more than 1 day; treatment - within 10-14 days, including the use of the investigational medicinal product for 5 days (from the first day of the basic therapy, daily). The total duration of observation is up to 14 days. Patients who completed participation in the study or dropped out of the study ahead of schedule were followed up by the attending physician in accordance with the rules for managing such patients for a medical institution.

Conditions

Interventions

TypeNameDescription
DRUGInterferon Gammainjection form

Timeline

Start date
2020-04-21
Primary completion
2020-06-17
Completion
2020-10-01
First posted
2022-05-23
Last updated
2022-05-27

Locations

1 site across 1 country: Russia

Source: ClinicalTrials.gov record NCT05386459. Inclusion in this directory is not an endorsement.