NCT05383521

Safety and Efficacy of Two Oral Tinidazole Regimens for Refractory Trichomonas Vaginitis

Oral Tinidazole Treatment of Refractory Trichomonas Vaginitis

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Shangrong Fan · Academic / Other
• Sex: Female
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

We compare two oral tinidazole regimens for refractory trichomonas vaginitis.

Detailed description

Refractory trichomonas vaginitis has become a clinical problem, which has a direct impact on the health and life of patients. Refractory trichomonas vaginitis is mainly caused by drug resistance of trichomonas. Drug resistant trichomonas has appeared China. Increasing the dosage of anti trichomonal drugs is the main treatment method at present. The aim of this study was to evaluate the efficacy and safety of two oral tinidazole regimens for refractory trichomonas vaginitis.

Conditions

• Trichomonas Vaginitis

Interventions

Type	Name	Description
DRUG	Tinidazole 56	Tinidazole , 2g， twice daily for 14 days. At the same time, metronidazole, 400 mg, once a day, vaginal administration, 14 days.
DRUG	Tinidazole 42	Tinidazole , 1g, three times daily for 14 days. At the same time, metronidazole, 400 mg, once a day, vaginal administration, 14 days.

Timeline

• Start date: 2025-12-01
• Primary completion: 2025-12-30
• Completion: 2025-12-30
• First posted: 2022-05-20
• Last updated: 2024-06-11

Locations

4 sites across 1 country: China