Clinical Trials Directory

Trials / Completed

CompletedNCT05381948

Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD)

A Phase 2, Multicenter, Prospective, Randomized, Double-Masked, Parallel Study of EYP-1901, a Tyrosine Kinase Inhibitor (TKI), Compared to Aflibercept in Subjects With Wet AMD

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
161 (actual)
Sponsor
EyePoint Pharmaceuticals, Inc. · Industry
Sex
All
Age
50 Years
Healthy volunteers
Not accepted

Summary

This is a phase 2 randomized, double -masked study comparing the efficacy of EYP-1901 at 2 dose levels: 2060 microgram (mcg) and 3090 mcg against aflibercept.

Detailed description

This study is evaluating the 2 doses of EYP-1901 against aflibercept in a randomized study.

Conditions

Interventions

TypeNameDescription
DRUGEYP-1901Intravitreal Injection
DRUGAflibercept 2mg/0.05mL Inj,OphIntravitreal Injection

Timeline

Start date
2022-06-30
Primary completion
2023-11-29
Completion
2024-04-24
First posted
2022-05-19
Last updated
2025-10-15
Results posted
2025-10-02

Locations

67 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05381948. Inclusion in this directory is not an endorsement.