Clinical Trials Directory

Trials / Active Not Recruiting

Active Not RecruitingNCT05380492

Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration

Phase 1/2a Dose Escalation Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration

Status
Active Not Recruiting
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
45 (estimated)
Sponsor
Perceive Biotherapeutics, Inc. · Industry
Sex
All
Age
50 Years
Healthy volunteers
Not accepted

Summary

This safety study comprises a dose escalation study of VOY-101, followed by a cohort of subjects randomized to the maximum tolerated dose arm, a lower dose arm, and control arm.

Detailed description

This is a prospective, multi-center safety phase 1/2a study to evaluate the safety of a single, unilateral intravitreal (IVT) injection of three dose levels of VOY-101 therapy in subjects with late-stage non-neovascular age-related macular degeneration (AMD).

Conditions

Interventions

TypeNameDescription
BIOLOGICALVOY-101Intravitreal injection of VOY-101

Timeline

Start date
2022-11-17
Primary completion
2025-11-01
Completion
2025-11-01
First posted
2022-05-19
Last updated
2024-04-11

Locations

3 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05380492. Inclusion in this directory is not an endorsement.