NCT05376449

Spinal Cord Injury - Exercise

The Effect of an Adaptive Exercise Program on Chronic Inflammation in Spinal Cord Injury

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: HealthPartners Institute · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Long lasting inflammation in the body is related to cardiovascular and respiratory disease, which are the two most common causes of death in people living with spinal cord injury (SCI). Individuals with SCI have been reported to have higher levels of inflammation when compared to healthy individuals. Exercise is a well-known method to reduce inflammation; however, people with SCI are often inactive. The main goal of this study is to determine whether a 12-week adaptive exercise program can reduce inflammation in people with SCI. Participants will be randomized to start exercise immediately or after a 12-week delay.

Conditions

• Spinal Cord Injuries

Interventions

Type	Name	Description
BEHAVIORAL	HealthPartners NeuroWell Exercise Program	A 12-week exercise program geared towards individuals with neurological disorders or injuries run by the Regions Hospital Rehabilitation department at the HealthPartners Neuroscience Center. The exercise programming will be designed by the exercise physiologists and adapted to individuals' abilities. Exercise prescriptions will be designed based on established guidelines, level and completeness of injury, individual functional ability, individual goals, and baseline exercise assessments. Program will consist of strength and endurance adaptive exercise.

Timeline

• Start date: 2022-05-09
• Primary completion: 2024-06-20
• Completion: 2024-09-13
• First posted: 2022-05-17
• Last updated: 2025-10-20
• Results posted: 2025-10-20

Locations

1 site across 1 country: United States