NCT05375357

Platelet Rich Fibrin in Soft Tissue Healing After Implant Uncovering

Evaluation of Healing Time and Postoperative Morbidity After Implant Uncovering With Vestibularly Repositioned Flap Associated With Leucocyte Platelet Rich Fibrin (L-PRF): a Randomized and Controlled Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: G. d'Annunzio University · Academic / Other
• Sex: All
• Age: 19 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This study represents a prospective, controlled and randomized clinical trial assessing the effects of L-PRF on the healing time of the donor area and on the patient's postoperative morbidity in the 4 weeks following the Apically Positioned Flap (APF) procedure in the uncovering phase of two-stage implants. A total of 40 patients were recruited and divided into two groups. The implant uncovering procedure in the test group was performed with APF and application of L-PRF on the donor area. Patients in the control group, on the other hand, were treated with APF alone, leaving the donor area to heal by secondary intention.

Conditions

• Healing Surgical Wounds

Interventions

Type	Name	Description
PROCEDURE	Application of L-PRF on the donor area	After implant uncovering procedure with apically positioned flap, the donor area is covered with a layer of L-PRF
PROCEDURE	Secondary intention healing of the donor area	After implant uncovering procedure with apically positioned flap, the donor area is left to heal by secondary intention

Timeline

• Start date: 2021-04-20
• Primary completion: 2022-07-30
• Completion: 2022-07-30
• First posted: 2022-05-16
• Last updated: 2022-12-19

Locations

1 site across 1 country: Italy