NCT05373459

Effect of a Third COVID-19 Booster Among Health Care Workers

Effect of a Third COVID-19 Booster on COVID-19 Infection Rate and Return to Works During Fifth Wave COVID-19 Among Health Care Workers

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 3,167 (actual)
• Sponsor: Hong Kong Sanatorium & Hospital · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

A new wave of COVID-19 infections, mainly caused by the Omicron/ Delta variant, has been sweeping the globe since the start of 2022. In response, the administration of a third dose of COVID-19 vaccine was considered to address potential waning immunity over time and reduced effectiveness against the Omicron/ Delta variant. The pandemic also resulted in many infections among health care workers (HCWs) and their households. In this study, a retrospective analysis would perform on risk of COVID-19 infection and their outcome in relation to their COVID-19 vaccination history by using the data repository from one of the Hong Kong private hospitals. HCWs were required to submit a standardized online self-declaration form for report of 1) demographic of the HCWs, 2) symptoms related history and 3) COVID-19 exposure history once they were COVID-19 confirmed by rapid antigen test against COVID-19 and/or polymerase chain reaction (PCR) test for COVID-19. Subsequent follow up such as contact tracing, COVID-19 PCR testing results of these HCWs and status of return to work were captured by the infection control team in a systematic manner.

Conditions

• COVID-19 Vaccines

Interventions

Type	Name	Description
BIOLOGICAL	Third COVID-19 booster	Third COVID-19 booster

Timeline

• Start date: 2022-05-16
• Primary completion: 2022-12-31
• Completion: 2022-12-31
• First posted: 2022-05-13
• Last updated: 2024-02-28

Locations

1 site across 1 country: Hong Kong