NCT05373290

A Cohort Study of Environmental Endocrine Disrupting Chemicals and Female Reproductive Health

Adverse Effects and Mechanism of Environmental Endocrine Disrupting Chemicals on Female Reproductive health--the Peking University and Environment Reproductive Health Cohort

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 2,000 (estimated)
• Sponsor: Peking University People's Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Infertility is a disease that seriously affects the physical and mental health of women of childbearing age. The incidence of infertility has been increasing in recent years. Studies have shown that the occurrence of infertility may be related to environmental endocrine disrupting substances. This project was designed to establish a cohort study on environmental endocrine disrupting substances and in vitro fertilization (IVF) treatment, collect blood, urine, semen, follicular fluid, granulosa cells, chorionic decidua biological specimens, and then follow up on the pregnancy outcomes. The concentration of disrupting substances was detected and then found the associations between environmental endocrine disrupting substances and female reproductive health.

Conditions

• IVF

Interventions

Type	Name	Description
OTHER	there is no intervention in the study	there is no intervention in the study

Timeline

• Start date: 2018-01-01
• Primary completion: 2022-12-01
• Completion: 2022-12-01
• First posted: 2022-05-13
• Last updated: 2022-05-13

Locations

1 site across 1 country: China