Trials / Completed
CompletedNCT05372601
Prebiotics and Stress Reduction in Women
The Effect of Galacto-oligosaccharides (GOS) on Self-perceived Stress in Apparently Healthy But Stressed Dutch Women: Randomized Controlled Study
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 124 (actual)
- Sponsor
- FrieslandCampina · Industry
- Sex
- Female
- Age
- 25 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
In modern life, many people state to experience stress. Women compared to men report more and higher levels of stress. Recent research found that supplementation of galactose-oligosaccharides (GOS) resulted in reduced anxiety levels in British female students with higher anxiety scores at baseline in self-reported trait anxiety. Moreover, supplementation of probiotics in germ-free rodents resulted in reduced levels of circulating corticosterone (cortisol in humans). These findings illustrate the potential of prebiotic supplementation, through the microbiota-gut-brain (MGB) axis, to improve mental health and wellbeing. The present study aims to study the effect of oligosaccharides on self-perceived stress.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Relax+ | Prebiotics, daily administered |
| DIETARY_SUPPLEMENT | Maltodextrin | Placebo, daily administered |
Timeline
- Start date
- 2022-02-17
- Primary completion
- 2022-06-18
- Completion
- 2022-06-18
- First posted
- 2022-05-13
- Last updated
- 2024-03-04
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT05372601. Inclusion in this directory is not an endorsement.