Trials / Completed
CompletedNCT05370261
Pharmacological Profile of Different Berberine Formulations, and Effects on Blood Sugar Levels
Comparing the Pharmacological Profile of Different Berberine Formulations, and Their Effects on Blood Sugar Levels
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 12 (actual)
- Sponsor
- Factors Group of Nutritional Companies Inc. · Industry
- Sex
- All
- Age
- 21 Years – 65 Years
- Healthy volunteers
- Accepted
Summary
The primary objective of this study is to evaluate the gastrointestinal absorption of berberine (hydrochloride) in a novel formulation in healthy adult volunteers by comparing it with free berberine (hydrochloride) formulation. Several pharmacokinetic parameters are compared. As secondary objective, the immediate or short-term effects of Berberine supplementation on blood sugar levels in healthy volunteers are evaluated via a glucose tolerance test (OGTT) using a portable glucometer.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Berberine LipoMicel | Berberine LipoMicel® soft-gels. Total dose of 500 mg of berberine |
| DIETARY_SUPPLEMENT | Regular Berberine hard-gels | Total dose of 500 mg of berberine |
Timeline
- Start date
- 2022-02-01
- Primary completion
- 2022-05-04
- Completion
- 2022-05-04
- First posted
- 2022-05-11
- Last updated
- 2023-02-13
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT05370261. Inclusion in this directory is not an endorsement.