Trials / Unknown
UnknownNCT05368610
Lesion Contiguity in Very High Power-short Duration Ablation
Effect of Very High Power-short Duration Ablation on Lesion Contiguity in Pulmonary Vein Isolation as Assessed by Late Gadolinium Enhancement Cardiovascular Magnetic Resonance
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 128 (estimated)
- Sponsor
- University of Barcelona · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- —
Summary
This observational trial investigates the effect of very high power-short duration radiofrequency ablation on lesion contiguity as assessed by late gadolinium enhancement cardiovascular magnetic resonance (LGE-CMR). Patients with paroxysmal or early persistent atrial fibrillation (AF) scheduled for pulmonary vein isolation (PVI) undergo point-by-point ablation using the QDOT micro catheter applying Qmode+ (90W over 4 seconds). All patients receive an LGE-CMR 3 months after the procedure for ablation lesion assessment. Contiguity of LGE-CMR-detected ablation lesions will be compared with a matched control group of patients that have undergone PVI accomplished by ablation index-guided ablation with 40 W following the CLOSE protocol.
Conditions
Timeline
- Start date
- 2022-03-10
- Primary completion
- 2023-06-01
- Completion
- 2023-06-01
- First posted
- 2022-05-10
- Last updated
- 2022-05-10
Locations
1 site across 1 country: Spain
Source: ClinicalTrials.gov record NCT05368610. Inclusion in this directory is not an endorsement.