NCT05366075

The Preventing Functional Decline in Acutely Hospitalized Older Patients (PREV_FUNC) Study

• Status: Recruiting
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 320 (estimated)
• Sponsor: Karolinska Institutet · Academic / Other
• Sex: All
• Age: 75 Years
• Healthy volunteers: Not accepted

Summary

This study aims to examine 1) if multicomponent exercise interventions (including both mobility and strengthening exercises) have effects on physical function compared to usual care in older adults, and 2) if a comprehensive multicomponent exercise program is more effective than a simple multicomponent exercise program including only walking and rising from a chair.

Detailed description

This is a three-armed randomized controlled trial, with two intervention groups (comprehensive and simple exercise program) and a control group receiving usual care. Participants aged ≥75 years will be included consecutively from geriatric medical wards of hospitals in Stockholm, Sweden. Assessments will be conducted at hospital admission, discharge and three months thereafter concerning physical function (primary outcome), activities of daily living, health-related quality of life, sarcopenia, and falls. Number of re-admissions and mortality will be registered up to 1 year after discharge.

Conditions

• Hospitalization
• Older Adults

Interventions

Type	Name	Description
OTHER	Intervention 1 (simple exercise program)	Up to four sessions per day (total duration 20-30 minutes/day). Performed at the hospital on all weekdays from baseline until hospital discharge (around 1 week). At discharge, the participants will be encouraged to continue with the exercise program at home.
OTHER	Intervention 2 (comprehensive exercise program)	Two daily sessions (morning and afternoon) of 20 minutes' duration each. Performed at the hospital on all weekdays from baseline until hospital discharge (around 1 week).

Timeline

• Start date: 2022-09-01
• Primary completion: 2025-06-01
• Completion: 2026-06-01
• First posted: 2022-05-09
• Last updated: 2024-12-20

Locations

1 site across 1 country: Sweden