NCT05365906

UTI Reference Standard: Delphi Method

Development of a Research Reference Standard for Urinary Tract Infection Using a Modified Delphi Technique

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 47 (actual)
• Sponsor: Leiden University Medical Center · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

This study is set up by an international core group consisting of infectious disease specialists, geriatricians, urologists, microbiologists, emergency physicians and primary care physicians to develop a consensus-based research definition of urinary tract infections. The absence of such a reference standard leads to misclassification bias and heterogeneity between studies making progress in the field of UTI difficult, for example with much needed near patient diagnostic tests.

Conditions

• Urinary Tract Infections

Interventions

Type	Name	Description
OTHER	Delphi-procedure consisting of four survey rounds	This study will use a modified Delphi approach, consisting of a set of iterative questionnaires. In round 1, an expert panel will grade the relevance of UTI-related items, after which a smaller core research team will compose a reference standard in a series of (online) meetings. In round 2, clinical vignettes will be used to party validate the reference standard and expert panel agreement with the new reference standard will be assessed.

Timeline

• Start date: 2022-04-12
• Primary completion: 2023-02-23
• Completion: 2023-02-23
• First posted: 2022-05-09
• Last updated: 2023-03-08

Locations

1 site across 1 country: Netherlands