NCT05364736

Effect of Prebiotics on Blood Pressure Management

An Interventional Study for the Effects of Highland Barley β-glucan on the Management of Hypertension and Cardiovascular Risk

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Sun Yat-sen University · Academic / Other
• Sex: All
• Age: 30 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This survey is designed to investigate the effect of highland barley β-glucan supplementation on the regulatory of blood pressure, gut microbiota and cardiovascular risk fators in subjects with hypertention.

Detailed description

Highland barley β-glucan belongs to the group of prebiotics and has been found to be associated with multiple health benefits. However, its protective role in subjects with hypertension are remain unclear. This study aims to examine the effect of 12-week prebiotics supplementation on blood pressure management in subjects with hypertension. By understanding the mechanism by which prebiotics exert the beneficial effects, we can better control the rising prevalence of hypertension, which is a major risk factor for cardiovascular diseases.

Conditions

• Hypertension
• Gastrointestinal Microbiome

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Highland barley β-glucan dietary supplement	100 mL oral liquid mainly containing highland barley β-glucan once daily for 12 weeks
OTHER	Placebo controls	Placebo with a similar appearance and taste to highland barley β-glucan supplement

Timeline

• Start date: 2022-10-17
• Primary completion: 2023-12-31
• Completion: 2030-12-31
• First posted: 2022-05-06
• Last updated: 2022-05-06

Locations

1 site across 1 country: China