NCT05363189

Optimizing Postoperative Recovery After Breast Reconstruction With Autologous Tissue (BestDIEP)

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 380 (estimated)
• Sponsor: Vastra Gotaland Region · Other Government
• Sex: Female
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

Women who have their breast reconstructed with autologous tissue seem to be more satisfied with their breast. However, autologous breast reconstruction entails a bigger operation, and the usage of more health care resources, than some other methods, such as implant-based techniques. The main objectives of the present study are to investigate if pre- peri- and postoperative protocols can be safely modified, so the operation demands less resources, while maintaining a low complication rate and a high patient satisfaction.

Conditions

• Breast Reconstruction
• Breast Cancer

Interventions

Type	Name	Description
PROCEDURE	Venous augmentation	Increasing the venous drainage of a deep inferior epigastric artery perforator (DIEP) flap by anastomosing the superficial inferior epigastric vein to the cephalic vein
PROCEDURE	Traditional ERAS (enhanced recovery after surgery) protocol	Pre-, peri-, and post-operative care as described in the ERAS protocol
PROCEDURE	Sahlgrenska recovery protocol	Pre-, peri-, and post-operative care as described in the Sahlgrenska recovery protocol
PROCEDURE	No venous augmentation	Traditional deep inferior epigastric artery perforator flap (DIEP)

Timeline

• Start date: 2022-05-02
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2022-05-05
• Last updated: 2025-07-03

Locations

1 site across 1 country: Sweden