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Active Not RecruitingNCT05362721

PV Loop & Coarctation Study

Assessment of the Impact of Transcatheter Stenting of Aortic Coarctation on the Left Ventricular Afterload and Work Using Left Ventricular Pressure Volume Loops

Status
Active Not Recruiting
Phase
Study type
Observational
Enrollment
21 (actual)
Sponsor
University of Minnesota · Academic / Other
Sex
All
Age
6 Years
Healthy volunteers
Not accepted

Summary

Coarctation of the aorta accounts for 4-7% of all congenital heart disease. While stent therapy, when feasible, is the standard of care for coarctation, it may not completely improve the work (and afterload) of the heart due to its effects on the elasticity of the aorta. This study will provide the information needed to understand the effects of current management on the cardiac mechanics and work.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTPressure-volume loop catheterThe cardiac catheterization procedure will be done according to standard protocol as part of the standard clinical care. This has become the standard of care in any patient in which it feasible and is performed with low risk.

Timeline

Start date
2019-06-04
Primary completion
2026-12-31
Completion
2026-12-31
First posted
2022-05-05
Last updated
2026-04-08

Locations

7 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT05362721. Inclusion in this directory is not an endorsement.

PV Loop & Coarctation Study (NCT05362721) · Clinical Trials Directory