NCT05361785

Fecal Microbiota Transplantation for Irritable Bowel Syndrome Associated Food Intolerance

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 45 (estimated)
• Sponsor: Helsinki University Central Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Previous studies have shown that stool transplantation (FMT) have positive effect in symptoms for some patients with irritable bowel syndrome (IBS). Studies have shown that it is possible by FMT to reverse the microbiome of the recipient's intestine in the direction of the microbiome of the donor. The effect on eating habits for engraftment of microbiome by FMT is unknown. The purpose of this study is to investigate whether FMT relieves FODMAP diet extension without worsening intestinal symptoms in IBS patients.

Detailed description

This is a plasebo controlled study in which we study the effect and safety of FMT in patients who have IBS and have used FODMAP diet. FMT is assessed by colonoscopy route and therafter the patietns receive twice FMT enema from healthy donor or plasebo..

Conditions

• Irritable Bowel Syndrome
• Fecal Microbiota Transplantation

Interventions

Type	Name	Description
BIOLOGICAL	FMT	FMT from healthy donor or placebo

Timeline

• Start date: 2022-04-30
• Primary completion: 2024-07-31
• Completion: 2026-07-31
• First posted: 2022-05-05
• Last updated: 2022-05-13

Locations

1 site across 1 country: Finland