NCT05361252

Stroke Volume Variation-guided Fluid Infusion in Major Liver Tumour Resection

Restrictive Versus Liberal Stroke Volume Variation-guided Fluid Infusion in Major Liver Tumour Resection: a Prospective Randomised Trial of Perioperative Quality of Care

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 118 (actual)
• Sponsor: Kaohsiung Veterans General Hospital. · Academic / Other
• Sex: All
• Age: 20 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Studies have demonstrated that the rate of change in stroke volume variation (SVV) can be used to determine the volume of body fluids during major abdominal surgery. Anaesthesiologists can use SVV as a guide for the appropriate administration of intraoperative fluids to improve postoperative prognoses. Liver surgery is a major abdominal operation, and the amount of blood lost is typically higher than that during other general abdominal surgeries. Blood loss is positively correlated with the intraoperative fluid infusion volume, and greater blood loss is associated with more postoperative complications. Additionally, comorbid liver disease or cirrhosis can increase the complexity of liver tumour resection, causing difficulty in assessing intravascular volume and determining the appropriate intraoperative infusion volume.

Conditions

• Fluid Management

Interventions

Type	Name	Description
PROCEDURE	SVV-guided fluid management	fluid will be guided by value of stroke volume variation

Timeline

• Start date: 2017-02-01
• Primary completion: 2018-12-31
• Completion: 2018-12-31
• First posted: 2022-05-04
• Last updated: 2022-07-01

Locations

1 site across 1 country: Taiwan