NCT05360329

Genicular Artery Embolization as Pain Treatment of Knee Osteoarthritis

Genicular Artery Embolization as Pain Treatment of Mild to Moderate Knee Osteoarthritis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 17 (actual)
• Sponsor: Rigshospitalet, Denmark · Academic / Other
• Sex: All
• Age: 30 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to investigate the safety and efficacy of geniculate artery embolization (GAE) as pain treatment in patients with mild to moderate knee osteoarthritis.

Detailed description

This is a single arm, prospective, pilot study investigating the safety and efficacy of GAE as pain treatment in patients with mild to moderate knee osteoarthritis. Patient related outcome measurements (PROMs), physical tests and several image modalities will be conducted. It may form the grounding for further research in the shape of a larger randomized clinical trial. The hypothesis is, that GAE will reduce synovitis and thereby pain in the patient group. This may secondary improve physical function and reduce consumption of analgesics.

Conditions

• Knee Osteoarthritis

Interventions

Type	Name	Description
PROCEDURE	Transarterial geniculate artery embolization	The procedure will be performed in local anaesthesia. An antegrade percutaneous transfemoral approach with super-selective catheterisation of geniculate neovesselswill be performed and subsequently the target will be pruned with microspherical embolic material.

Timeline

• Start date: 2022-09-20
• Primary completion: 2023-12-19
• Completion: 2023-12-19
• First posted: 2022-05-04
• Last updated: 2024-12-20

Locations

1 site across 1 country: Denmark