Trials / Recruiting
RecruitingNCT05359887
PET-study on the Role of the Reward System in Weight Loss After Bariatric Surgery
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- Sponsor
- University Medical Center Groningen · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Bariatric surgery (BS) is currently the most effective treatment in severe obesity. However, a considerable percentage of patients undergoing BS fail to lose sufficient weight or regain weight after initial weight loss during long-term follow-up, which may be attributed to personality traits and pathological eating behaviour. Previous positron emission tomography (PET) studies have shown reduced dopamine D2 receptor availability in obese patients and upregulation of this availability following successful BS in the brain's reward system. Dopamine D2 receptor availability in patients with unsuccessful BS has not been investigated to date.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | standardized liquid mixed meal Nutridrink® | Administration of food in controlled situation |
Timeline
- Start date
- 2022-12-01
- Primary completion
- 2024-12-31
- Completion
- 2024-12-31
- First posted
- 2022-05-04
- Last updated
- 2024-05-14
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT05359887. Inclusion in this directory is not an endorsement.