NCT05358743

Effect of Probiotics on Oral Candida Among Denture Wearers

Effect of Probiotics on Oral Candida Colonization Level in Complete Denture Wearers (Randomized Controlled Clinical Trial)

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Hams Hamed Abdelrahman · Academic / Other
• Sex: All
• Age: 40 Years
• Healthy volunteers: Not accepted

Summary

Forty-eight denture wearers with detectable levels of candida colonization without clinical symptoms will be randomly allocated into two groups: probiotics and placebo. All patients will take a daily dose of chewable tablets (probiotics or placebo according to the assigned group) for 8 weeks. Samples of mouth rinse will be collected from patients at baseline, 4 weeks from the beginning of the intervention, 8 weeks (the end of intervention), and after another 4 weeks for post-intervention follow up. Samples will be tested for both candida count and candida species identification

Conditions

• Oral Candida Albicans Infection

Interventions

Type	Name	Description
OTHER	Probiotic group	Participants will use the probiotic product once daily (1 tablet/day) for 8 weeks
OTHER	Placebo group	Patients will chew placebo products (blueberry tablets) once daily (1 tablet/day) for 8 weeks.

Timeline

• Start date: 2022-05-01
• Primary completion: 2023-01-30
• Completion: 2023-01-30
• First posted: 2022-05-03
• Last updated: 2023-01-12

Locations

1 site across 1 country: Egypt