Clinical Trials Directory

Trials / Recruiting

RecruitingNCT05357768

Global collaboRAtion on CIC-DUX4, BCOR-CCN3, High-grade Undifferentiated Round Cell Sarcoma (URCS) Project

Status
Recruiting
Phase
Study type
Observational
Enrollment
260 (estimated)
Sponsor
Istituto Ortopedico Rizzoli · Academic / Other
Sex
All
Age
Healthy volunteers

Summary

Experimental study with biological material : case series review of clinical and histological data

Detailed description

This is a multicenter retrospective and prospective study that will analyze all cases with a diagnosis of Undifferentiated round cell sarcomas from 01 January 1983 and all new cases referring to each participant site.

Conditions

Interventions

TypeNameDescription
OTHERdata collection and analysis on Formalin-fixed paraffin embedded tissue and/or frozen tumoral tissueFormalin-fixed paraffin embedded tissue and/or frozen tumoral tissue of cases negative for all Ewing's sarcoma molecular fusions, will be analyzed for the presence of CIC-DUX4 / BCOR-CCNB3 translocations fusion at each Institution. Treatment, outcome, and prognostic factors will be related with the molecular re-classification.

Timeline

Start date
2019-06-11
Primary completion
2026-12-31
Completion
2028-12-31
First posted
2022-05-03
Last updated
2025-05-30

Locations

1 site across 1 country: Italy

Source: ClinicalTrials.gov record NCT05357768. Inclusion in this directory is not an endorsement.