NCT05357521

Interplay Between Oxytocin and Cortisol During Stress in Borderline Personality Disorder

Feasibility and Preliminary Data on the Interplay Between Oxytocin and Cortisol During Stress in Borderline Personality Disorder

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: University of Geneva, Switzerland · Academic / Other
• Sex: Female
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

This study aims to determine the feasibility and preliminary data on the interaction between oxytocin and cortisol during stress in borderline personnality disorder.

Detailed description

The investigators will recruit 50 female patients with borderline personnality disorder and 50 controls with no psychiatric diagnosis, aged between 18 and 25 years old. salivary cortisol daily curve ( 6 measures during the day) will be measured in participant's naturalistic environnement, together with salivary oxytocin. In addition, salivary oxytocin and cortisol will be measured during a psychosocial stress task and recovery.

Conditions

• Borderline Personality Disorder
• Oxytocin

Interventions

Type	Name	Description
OTHER	stress test	TSST- psychosocial stress test

Timeline

• Start date: 2022-03-01
• Primary completion: 2025-03-30
• Completion: 2025-04-30
• First posted: 2022-05-03
• Last updated: 2025-05-16

Locations

1 site across 1 country: Switzerland