NCT05356156

The Safe Study of Routine Closure of Mesenteric Defects Versus Non-closure After Radical Gastrectomy

A Multicenter, Randomized, Controlled Clinical Trial of the Safety of Mesenteric Defects Closure After Radical Gastrectomy

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,968 (estimated)
• Sponsor: The First Affiliated Hospital with Nanjing Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

To compare the incidence of internal hernia, overall survival and short-term surgical safety of routine closure of the surgically created mesenteric defects versus non-closure for patients with adenocarcinoma of the gastric or esophagogastric junction who underwent radical gastrectomy (D1+/D2 lymph node dissection).

Conditions

• Gastric Cancer

Interventions

Type	Name	Description
PROCEDURE	Closure of the mesenteric defects	The surgically created mesenteric defects will be closed after radical gastrectomy with D1+/D2 lymph node dissection.
PROCEDURE	Non-closure of the mesenteric defects	The surgically created mesenteric defects will not be closed after radical gastrectomy with D1+/D2 lymph node dissection.

Timeline

• Start date: 2022-04-01
• Primary completion: 2027-03-01
• Completion: 2027-03-01
• First posted: 2022-05-02
• Last updated: 2022-05-02

Locations

1 site across 1 country: China