NCT05355610

Vestibular Rehabilitation With Intratympanic Drug Therapy in Meniere's Disease

Objective Vestibular Evaluation & Rehabilitation With Intratympanic Dexamethasone and Gentamicin in Meniere's Disease

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 93 (estimated)
• Sponsor: Combined Military Hospital Quetta · Academic / Other
• Sex: All
• Age: 24 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Intractable symptoms of Meniere's disease will be treated with intratympanic steroids. At the same time intratympanic dexamethasone will be used to rescue hearing

Detailed description

For Alleviation of Intractable symptoms of Meniere's disease will be treated with intratympanic steroids. Measured with pre and post therapy vestibular severity index. At the same time intratympanic dexamethasone will be used to rescue hearing measured with speech reception threshold and speech discrimination threshold

Conditions

• Vestibular Disorder Preservation

Interventions

Type	Name	Description
DRUG	Gentamicin	Intratympanic gentamicin and dexamethasone administered in two doses one week apart
DRUG	Dexamethasone	Intratympanic gentamicin and dexamethasone administered in two doses one week apart

Timeline

• Start date: 2021-04-01
• Primary completion: 2022-04-22
• Completion: 2022-05-30
• First posted: 2022-05-02
• Last updated: 2022-05-02

Locations

1 site across 1 country: Pakistan