NCT05354401

Heated Humidified High Flow Nasal Cannula Oxygen in Obstructive Sleep Apnea in Adolescents

Use of Heated Humidified High Flow Nasal Cannula Oxygen in Obstructive Sleep Apnea in Adolescents With Obesity and Complex Medical Conditions

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: The Hospital for Sick Children · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The research study is being done to test heated humidified high-flow air (HHF), as a treatment for OSA.

Conditions

• Obesity
• Obstructive Sleep Apnea (Moderate to Severe)
• Central Sleep Apnea

Interventions

Type	Name	Description
OTHER	HHF	HHF is an integrated flow generator that delivers heated and humidified air or oxygen at high flow rates via a soft nasal cannula using an open circuit. HHF via the Fisher and Paykel myAIRVO 2 device will be initiated as per The Hospital for Sick Children's sleep laboratory standard protocol by a sleep technician or respiratory therapist (RT) during an overnight polysomnography. Nasal prongs will be selected that are less than fifty percent of the subject's nares. The lowest flow rate of HHF will be selected and titrated upwards until clinical effect is achieved, to a maximum flow of 60L/minute, as per standard clinical care.

Timeline

• Start date: 2019-03-01
• Primary completion: 2023-03-02
• Completion: 2023-03-02
• First posted: 2022-04-29
• Last updated: 2024-01-18

Locations

1 site across 1 country: Canada